HoxPred Home
About HoxPred
HoxPred is an automated method that classifies Hox proteins in their groups of homology, based on their homeodomain region. This method relies on a discriminant analysis that classifies Hox proteins according to their scores for a combination of protein profiles. New ! Datab'Hox is a comprehensive database of HoxPred classification of thousands of metazoan homeodomain sequences.References
New !Thomas-Chollier M, Ledent V, Leyns L, Vervoort M "A non-tree-based comprehensive study of metazoan Hox and ParaHox genes prompts new insights into their origin and evolution", BMC Evol Biol, 10:73 2010 [Full text]
Thomas-Chollier M, Ledent V "Comparative phylogenomic analyses of teleost fish Hox gene clusters: lessons from the cichlid fish Astatotilapia burtoni: comment", BMC Genomics, 9:35 2008 [Pubmed] [Full text]
Thomas-Chollier M, Leyns L, Ledent V "HoxPred: automated classification of Hox proteins using combinations of generalised profiles", BMC Bioinformatics, 8: 247 2007 [Pubmed] [Full text]
New ! Publications using HoxPred
Guo et al. "Hox genes of the Japanese eel Anguilla japonica and Hox cluster evolution in teleosts." J. Exp. Zool. (2009) vol. 9999B [Pubmed]
Running HoxPred
HoxPred is available with a Web interface on this website.HoxPred is also accessible programmatically via SOAP access.
Developer
HoxPred was developed by Morgane Thomas-Chollier during her PhD thesis.Obtaining Hoxpred
This software is OSI Certified Open Source Software .
Click here to download HoxPred.
Contacts
Morgane Thomas-Chollier
Email: morgane[at]bigre.ulb.ac.be
Full contact info: Homepage
Prof. Dr Luc Leyns
Vrije Universiteit Brussels (VUB)
Laboratory of Cell Genetics
Pleinlaan 2
1050 Brussels
BELGIUM
Phone: +32 2 629 34 43
Email: lleyns[at]vub.ac.be
This work was also conducted by Dr Valerie Ledent, formely from the Belgian EMBnet Node. Email: Valerie.Ledent[at]ulb.ac.be